Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848980 | 0.89 | MEN1 (0.46) | EPHX1PNMTMEN1ALDH1A1CYP1A2 | |
| SCHEMBL27849010 | 0.83 | EPHX1 (0.48) | EPHX1PNMTMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10216797 | 0.82 | PNMT (0.46) | PNMTCYP1A2CYP3A4CES2MMP7 | |
| Hydrochloric Acid SCHEMBL382000 | 0.81 | PNMT (0.44) | EPHX1PNMTCYP1A2CYP3A4CES2 | |
| SCHEMBL23539801 | 0.80 | CYP1A2 (0.56) | EPHX1PNMTMEN1ALDH1A1CYP1A2 | |
| SCHEMBL3446920 | 0.79 | KCNQ3 (0.44) | PNMTMEN1ALDH1A1CYP1A2POLB | |
| SCHEMBL27865909 | 0.78 | PNMT (0.62) | EPHX1PNMTMEN1ALDH1A1CYP1A2 | |
| SCHEMBL30699967 | 0.77 | PNMT (0.53) | EPHX1PNMTMEN1ALDH1A1CYP1A2 | |
| SCHEMBL30219768 | 0.77 | PNMT (0.53) | EPHX1PNMTMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10216755 | 0.75 | PTPRB (0.45) | MEN1CYP1A2POLBCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102438990-A | Substituted 2-acetamido-5-aryl-1, 2, 4-triazolones and use thereof | BAYER SCHERING PHARMA AG | 2012-05-02 | — | — | CN | disclosed |