Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119243 | 0.86 | TRPM8 (0.73) | TRPM8 | |
| SCHEMBL118985 | 0.82 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL119113 | 0.81 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL118337 | 0.81 | TRPM8 (0.81) | TRPM8 | |
| SCHEMBL121423 | 0.81 | TRPM8 (0.75) | TRPM8 | |
| SCHEMBL118619 | 0.81 | TRPM8 (0.82) | TRPM8 | |
| SCHEMBL120522 | 0.81 | TRPM8 (0.81) | TRPM8 | |
| SCHEMBL120722 | 0.81 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL119664 | 0.80 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL119000 | 0.80 | TRPM8 (1.00) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102427810-A | Sulfamoylbenzoic acid derivatives as TRPM8 antagonists | RAQUALIA PHARMA INC | 2012-04-25 | — | — | CN | disclosed |