Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797001 | 0.89 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL27866133 | 0.88 | PTGDR2 (0.48) | PTGDR2MCL1FFAR1TTR | |
| SCHEMBL27849062 | 0.86 | PTGDR2 (0.55) | PTGDR2 | |
| SCHEMBL1333653 | 0.84 | PTGDR2 (0.58) | PTGDR2MCL1TTR | |
| SCHEMBL28330663 | 0.84 | PTGDR2 (0.58) | PTGDR2MCL1TTR | |
| SCHEMBL1331643 | 0.81 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL1333658 | 0.79 | PTGDR2 (0.52) | PTGDR2MCL1TTR | |
| SCHEMBL1332548 | 0.79 | PTGDR2 (0.71) | PTGDR2 | |
| SCHEMBL2392953 | 0.78 | PTGDR2 (0.47) | PTGDR2MCL1FFAR1TTRCHRM1 | |
| SCHEMBL3928430 | 0.78 | PTGDR2 (0.50) | PTGDR2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102557971-A | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2012-07-11 | — | — | CN | claimed |
| CN-101014564-B | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2012-05-09 | — | — | CN | claimed |
| CN-102557971-A | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2012-07-11 | — | — | CN | disclosed |
| CN-101014564-B | Substituted acids for the treatment of respiratory diseases | ASTRAZENECA AB | 2012-05-09 | — | — | CN | disclosed |