Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SCN2B | O60939 | 1/20 | 0.38 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997584 | 0.87 | SCN9A (0.50) | SCN9A | |
| SCHEMBL19075585 | 0.78 | SCN9A (0.43) | SCN9ACYP2C9CYP3A4SCN2BSCN1B | |
| Tert-Butyl Formate SCHEMBL27849369 | 0.76 | SCN9A (0.41) | SCN9ACYP2C9CYP3A4SCN2BSCN1B | |
| SCHEMBL17428427 | 0.76 | SCN9A (0.42) | SCN9AHTR2AHTR2C | |
| SCHEMBL1745322 | 0.71 | SCN9A (0.51) | SCN9ACYP2C9CYP3A4 | |
| SCHEMBL19084060 | 0.71 | SCN9A (0.41) | SCN9ACYP2C9CYP3A4SCN2BSCN1B | |
| SCHEMBL27849364 | 0.71 | CHRNB2 (0.44) | SCN9AHTR2C | |
| SCHEMBL17428615 | 0.68 | SCN9A (0.52) | SCN9ACYP2C9CYP3A4SCN2BSCN1B | |
| SCHEMBL19075822 | 0.68 | SCN9A (0.52) | SCN9ACYP2C9CYP3A4SCN2BSCN1B | |
| SCHEMBL28816431 | 0.67 | SCN9A (0.50) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102348697-B | Sulfonamide derivatives | PFIZER LTD | 2014-12-10 | — | — | CN | disclosed |
| CN-102348697-A | Sulfonamide derivatives | PFIZER LTD | 2012-02-08 | — | — | CN | disclosed |