Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.79 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinimide SCHEMBL28635055 | 1.00 | CRBN (0.79) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL1326078 | 0.89 | CRBN (1.00) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL1600526 | 0.89 | — | — | |
| Succinimide SCHEMBL1466558 | 0.89 | — | — | |
| Succinimide SCHEMBL8361206 | 0.89 | CRBN (1.00) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL774 | 0.89 | — | — | |
| Biphenyl SCHEMBL7154019 | 0.86 | CRBN (0.58) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL9336599 | 0.85 | — | — | |
| Succinimide SCHEMBL10709037 | 0.85 | — | — | |
| Succinimide SCHEMBL20640078 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602872-A | Compositions and methods for treating cancer | 艾丽塔生物治疗剂公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-101916024-A | Preparation method of electrophoretic liquid containing two-way phoresis particles | UNIV ZHEJIANG | 2010-12-15 | — | — | CN | disclosed |