Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinimide SCHEMBL28635055 | 0.86 | CRBN (0.79) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL27849600 | 0.86 | CRBN (0.79) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL10852828 | 0.82 | CRBN (0.55) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL28715844 | 0.80 | CRBN (0.52) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Toluene SCHEMBL8371012 | 0.80 | CRBN (0.52) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Biphenyl SCHEMBL27603297 | 0.79 | CRBN (0.58) | CRBNNPC1SMN1; SMN2ALDH1A1LMNA | |
| Diphenylsulfane SCHEMBL4855555 | 0.78 | CRBN (0.50) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| (Z)-1,2-Diphenylethene SCHEMBL10997055 | 0.78 | CRBN (0.50) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL28472780 | 0.78 | CRBN (0.50) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| (Z)-1,2-Diphenylethene SCHEMBL10997053 | 0.78 | CRBN (0.50) | CRBNNPC1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528603-B1 | Alternating vinyloxy phosphonate and N-substituted maleimide groups; use in metal chelation and in forming multilayer thin films | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2003-03-04 | — | — | US | disclosed |