Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850001 | 1.00 | CYP4A11 (0.51) | CYP4A11CYP4F2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL27850003 | 0.96 | CYP4F2 (0.57) | CYP4A11CYP4F2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL5662951 | 0.88 | CYP4F2 (0.59) | CYP4A11CYP4F2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL6671931 | 0.88 | ALDH1A1 (0.49) | MTNR1AMTNR1BALDH1A1MAPTHDAC1 | |
| SCHEMBL3165356 | 0.86 | PTGDR2 (0.56) | CYP4A11CYP4F2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL3165037 | 0.86 | PTGDR2 (0.56) | CYP4A11CYP4F2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL7228518 | 0.85 | ALDH1A1 (0.47) | MTNR1BALDH1A1MAPT | |
| SCHEMBL2174618 | 0.85 | ALDH1A1 (0.47) | MTNR1BALDH1A1MAPT | |
| SCHEMBL14157560 | 0.84 | ALDH1A1 (0.44) | MTNR1AMTNR1BALDH1A1MAPTHDAC1 | |
| SCHEMBL14157559 | 0.84 | ALDH1A1 (0.44) | MTNR1AMTNR1BALDH1A1MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102442941-A | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2012-05-09 | — | — | CN | disclosed |