Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 8/20 | 0.64 |
| ▸ | GSK3B | P49841 | 8/20 | 0.64 |
| ▸ | FLT3 | P36888 | 8/20 | 0.63 |
| ▸ | SRC | P12931 | 6/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.63 |
| ▸ | JAK2 | O60674 | 5/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.63 |
| ▸ | KDR | P35968 | 4/20 | 0.63 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.63 |
| ▸ | PLK1 | P53350 | 4/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.63 |
| ▸ | PRKACA | P17612 | 4/20 | 0.63 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.63 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.63 |
| ▸ | SYK | P43405 | 1/20 | 0.63 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10304368 | 1.00 | GSK3A (0.64) | GSK3AGSK3BFLT3SRCPIK3CG | |
| SCHEMBL18052124 | 0.89 | GSK3A (0.53) | GSK3AGSK3BFLT3SRCPIK3CG | |
| SCHEMBL8942746 | 0.89 | — | — | |
| SCHEMBL17771573 | 0.89 | GSK3A (0.56) | GSK3AGSK3BFLT3SRCPIK3CG | |
| SCHEMBL21634630 | 0.89 | CDK2 (0.60) | GSK3AGSK3BFLT3SRCPIK3CG | |
| SCHEMBL21657643 | 0.89 | CDK2 (0.60) | GSK3AGSK3BFLT3SRCPIK3CG | |
| SCHEMBL21634627 | 0.89 | CDK2 (0.60) | GSK3AGSK3BFLT3SRCPIK3CG | |
| SCHEMBL10304390 | 0.88 | — | — | |
| SCHEMBL20643343 | 0.88 | GSK3A (0.59) | GSK3AGSK3BFLT3SRCPIK3CG | |
| Hydrochloric Acid SCHEMBL21634624 | 0.88 | CDK2 (0.59) | GSK3AGSK3BFLT3SRCPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102458408-A | Inhibitors of influenza virus replication | VERTEX PHARMA | 2012-05-16 | — | — | CN | disclosed |