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Lindane

Lindane

SCHEMBL2785151

C=CC(=O)O.Cl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl.OCC(CO)(CO)COCC(CO)(CO)CO.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

823298382338688239847Rdl1Rdl2Rdl3

The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachlorophenol SCHEMBL301602 0.94 ALDH1A1 (0.40) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Pentachlorophenol SCHEMBL2178192 0.89 ALDH1A1 (0.36) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Pentachlorophenol SCHEMBL20267956 0.89 ALDH1A1 (0.36) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Pentachlorophenol SCHEMBL18114673 0.89 ALDH1A1 (0.36) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Pentachlorophenol SCHEMBL21381899 0.84 ALDH1A1 (0.33) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Pentachlorophenol SCHEMBL1702812 0.81 ALDH1A1 (0.44) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Acrylic Acid SCHEMBL11137999 0.79 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Acrylic Acid SCHEMBL301603 0.79 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Acrylic Acid SCHEMBL701228 0.79 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Acrylic Acid SCHEMBL740134 0.79 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2221348-B1 Pigment dispersion composition, colored curable composition, color filter, liquid crystal display device and solid-state image sensor FUJIFILM CORP (JP) 2016-11-30 — — EP disclosed
EP-2221348-A2 Pigment dispersion composition, colored curable composition, color filter, liquid crystal display device and solid-state image sensor FUJIFILM Corporation (JP) 2010-08-25 — — EP disclosed
US-7488230-B2 Manufacturing method of display panel and sealing layer material thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-02-10 — — US disclosed
US-20070173166-A1 Manufacturing method of display panel and sealing layer material thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2007-07-26 — — US disclosed