SCHEMBL278516

SCHEMBL278516

Oc1cc(O)cc(-c2c(O)cc(O)cc2O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 1.00
BACE1 P56817 1/20 0.50
ABL1 P00519 4/20 0.46
ABCB1 P08183 4/20 0.46
BCR P11274 4/20 0.46
GAA P10253 1/20 0.42
FASN P49327 1/20 0.40
TDP1 Q9NUW8 2/20 0.38
BCL2 P10415 1/20 0.37
MCL1 Q07820 1/20 0.37
LCK P06239 1/20 0.36
MEN1 O00255 2/20 0.36
CYP3A4 P08684 2/20 0.36
KMT2A Q03164 2/20 0.36
HPGD P15428 1/20 0.36
NPC1 O15118 2/20 0.36
TP53 P04637 2/20 0.36
MAPK1 P28482 2/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29286369 0.82 NQO1 (0.70) NQO1BACE1TDP1BCL2MCL1
SCHEMBL13297165 0.82 NQO1 (0.68) NQO1BACE1ABL1ABCB1BCR
SCHEMBL2620531 0.82 NQO1 (0.68) NQO1GAATDP1LCKMEN1
SCHEMBL321298 0.79 NQO1 (0.65) NQO1BACE1FASNTDP1BCL2
SCHEMBL9243327 0.78 NQO1 (0.61) NQO1BACE1ABL1ABCB1BCR
SCHEMBL5890294 0.77 NQO1 (0.62) NQO1ABL1ABCB1BCRMEN1
SCHEMBL82736 0.76 NQO1 (0.61) NQO1TDP1MCL1LCKMEN1
SCHEMBL14087817 0.76 NQO1 (0.61) NQO1ESR1ESR2
SCHEMBL19668045 0.76 NQO1 (0.61) NQO1CYP3A4ESR1ESR2ALDH1A1
SCHEMBL14087818 0.76 NQO1 (0.61) NQO1BACE1ABCB1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005693-A Application of Jiaweidanzhi Xiaoyao powder or extract thereof in preparation of medicines for treating depression complicated with ulcerative colitis 河南中医药大学 2026-05-12 CN claimed
EP-4727986-A1 ABRASIVE ARTICLE August Rüggeberg GmbH & Co. KG (DE) 2026-04-22 EP claimed
WO-2025131235-A1 ABRASIVE ARTICLE AUGUST RÜGGEBERG GMBH & CO. KG (DE) 2025-06-26 WO claimed
CN-119439618-A Negative photosensitive resin composition, preparation method thereof and hardening film 深圳市道尔顿电子材料股份有限公司 2025-02-14 CN claimed
EP-4119631-A1 ADHESIVE COMPOSITION, RUBBER-ORGANIC FIBER CORD COMPOSITE, AND TIRE BRIDGESTONE CORPORATION (JP) 2023-01-18 EP claimed
CN-113736036-B Multi-arm polycarboxylate superplasticizer and preparation method thereof 成都奥莱特时代新材料有限公司 2022-06-10 CN claimed
US-20090081589-A1 THICK FILM RESISTS MERCK PATENT GMBH (DE) 2009-03-26 US claimed
CN-122095024-A Flame-retardant aromatic polycarbonate resin composition and molded article thereof 2026-05-26 CN disclosed
WO-2026100296-A1 FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN MASTER BATCH AND METHOD FOR MANUFACTURING SAME 信越化学工業株式会社 2026-05-15 WO disclosed
CN-122005693-A Application of Jiaweidanzhi Xiaoyao powder or extract thereof in preparation of medicines for treating depression complicated with ulcerative colitis 河南中医药大学 2026-05-12 CN disclosed
US-12617892-B2 Application of the ring-opening of uretdiones at low temperature and ambient atmosphere BASF SE (DE) 2026-05-05 US disclosed
EP-4407003-B1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LTD (JP) 2026-04-29 EP disclosed
EP-4727986-A1 ABRASIVE ARTICLE August Rüggeberg GmbH & Co. KG (DE) 2026-04-22 EP disclosed
EP-0443533-A2 Positive photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP disclosed
EP-0429954-A1 Mixture of predominantly polynuclear polyfunctional phenols and its use HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-05 EP disclosed
EP-0385442-A1 Positive-working photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1990-09-05 EP disclosed
US-3976488-A COUPLER, EXTENDER, DISPERSION MEDIUM MITA INDUSTRIAL COMPANY, LTD. (JA) 1976-08-24 US disclosed
US-3950171-A THERMOPLASTIC RESIN DIAZONIUM SALT MITA INDUSTRIAL CO. LTD. (JA) 1976-04-13 US disclosed
US-3948661-A Process for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LTD. (JA) 1976-04-06 US disclosed
US-3944422-A Photosensitive material in use for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LIMITED (JA) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617892-B2 Application of the ring-opening of uretdiones at low temperature and ambient atmosphere UQCRB, SCO2, UTS2R NQO1 675/4885BACE1 3296/4885ABL1 3694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.