Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789213 | 0.72 | — | — | |
| SCHEMBL26431999 | 0.67 | TSHR (0.40) | ALDH1A1TSHR | |
| SCHEMBL5541010 | 0.66 | MAPT (0.32) | ALDH1A1 | |
| SCHEMBL197101 | 0.65 | TSHR (0.38) | ALDH1A1TSHR | |
| SCHEMBL3378298 | 0.65 | TSHR (0.38) | ALDH1A1TSHR | |
| SCHEMBL9122838 | 0.65 | LMNA (0.32) | ALDH1A1TSHR | |
| SCHEMBL85493 | 0.64 | TSHR (0.57) | ALDH1A1TSHR | |
| SCHEMBL27408827 | 0.62 | — | — | |
| SCHEMBL20993532 | 0.62 | CA1 (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL28635066 | 0.61 | TSHR (0.53) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102421760-A | Dihydropyrimidinones useful as BACE2 inhibitors | HOFFMANN LA ROCHE | 2012-04-18 | — | — | CN | disclosed |