SCHEMBL2785208

SCHEMBL2785208

C=Cc1ccccc1C(C)(C)CC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
SHBG P04278 1/20 0.34
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RIPK1 Q13546 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30540422 0.82 ALDH1A1 (0.39) ALDH1A1TSHRTDP1
SCHEMBL2789090 0.82 ALDH1A1 (0.39) ALDH1A1TSHRTDP1
SCHEMBL3477029 0.81 TAAR1 (0.45) ALDH1A1TSHRTDP1
SCHEMBL6853084 0.79 CNR2 (0.42) ALDH1A1TSHR
SCHEMBL27805 0.77 ALDH1A1 (0.50) ALDH1A1TSHRTDP1
SCHEMBL29801228 0.77 ALDH1A1 (0.50) ALDH1A1TSHRTDP1
SCHEMBL7141124 0.75 ALDH1A1 (0.43) ALDH1A1TSHRTDP1
Benzene SCHEMBL11667348 0.75 ALDH1A1 (0.48) ALDH1A1TSHRTDP1RIPK1
SCHEMBL26099050 0.74 ALDH1A1 (0.39) ALDH1A1TSHRTDP1
SCHEMBL2948538 0.74 ALDH1A1 (0.41) ALDH1A1TSHRTDP1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100112021-A1 SUSTAINED-RELEASE COMPOSITION DOW GLOBAL TECHNOLOGIES LLC 2010-05-06 US disclosed
US-20100047353-A1 HAIR CARE COMPOSITION DOW GLOBAL TECHNOLOGIES LLC 2010-02-25 US disclosed
EP-2139448-A1 HAIR CARE COMPOSITION Dow Global Technologies Inc. (US) 2010-01-06 EP disclosed
EP-2139444-A2 SUSTAINED-RELEASE COMPOSITION Dow Global Technologies Inc. (US) 2010-01-06 EP disclosed
WO-2008115961-A2 SUSTAINED-RELEASE COMPOSITION DOW GLOBAL TECHNOLOGIES INC. (US) 2008-09-25 WO disclosed
WO-2008116036-A1 HAIR CARE COMPOSITION DOW GLOBAL TECHNOLOGIES INC. (US) 2008-09-25 WO disclosed
EP-0516766-A4 COSMETIC LOTION 1993-03-24 EP disclosed
EP-0516766-A1 COSMETIC LOTION DowBrands Inc. (US) 1992-12-09 EP disclosed
WO-1992000719-A1 MAKEUP COMPOSITION DOWBRANDS INC. (US) 1992-01-23 WO disclosed
WO-1992000724-A1 COSMETIC LOTION DOWBRANDS INC. (US) 1992-01-23 WO disclosed
US-4619826-A CROSSLINKED AND UNCROSSLINKED ADDITION POLYMERS THE DOW CHEMICAL COMPANY (US) 1986-10-28 US disclosed
US-4489058-A INTERPOLYMER OF VINYLAROMATIC, ACRYLATE, VINYL ESTER AND/OR DIOLEFIN OR HOMOPOLYMER OF DIOLEFIN THE DOW CHEMICAL COMPANY (US) 1984-12-18 US disclosed