Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 11/20 | 0.56 |
| ▸ | ATM | Q13315 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27965460 | 0.91 | PLG (0.45) | PLGCCR3GABRA1GABRG2GABRB3 | |
| SCHEMBL27852916 | 0.91 | PLG (0.55) | PLGATMGABRA1GABRG2GABRB3 | |
| SCHEMBL27965499 | 0.90 | PLG (0.45) | PLGGABRA1GABRG2GABRB3 | |
| SCHEMBL27965394 | 0.90 | PLG (0.45) | PLGGABRA1GABRG2GABRB3 | |
| SCHEMBL27853055 | 0.89 | PLG (0.58) | PLGGABRA1GABRG2GABRB3 | |
| SCHEMBL27853064 | 0.89 | PLG (0.44) | PLG | |
| SCHEMBL27965386 | 0.88 | PLG (0.41) | PLGGABRA1GABRG2GABRB3 | |
| SCHEMBL27965393 | 0.87 | PLG (0.45) | PLGGABRA1GABRG2GABRB3 | |
| SCHEMBL27965479 | 0.87 | PLG (0.45) | PLGSLC6A4GABRA1GABRG2GABRB3 | |
| SCHEMBL27853079 | 0.87 | PLG (0.42) | PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459246-B | Isoxazol-3 (2H) -one analogs as therapeutic agents | ASTRAZENECA AB | 2014-05-07 | — | — | CN | disclosed |
| CN-102459246-A | Isoxazol-3 (2H) -one analogs as therapeutic agents | ASTRAZENECA AB | 2012-05-16 | — | — | CN | disclosed |