Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864110 | 0.82 | LMNA (0.61) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL28297350 | 0.81 | TDP1 (0.63) | NPC1RAB9ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL21007 | 0.80 | CYP3A4 (0.69) | SMN1; SMN2LMNACYP3A4ALDH1A1KDM4E | |
| Benzene SCHEMBL28207781 | 0.80 | CYP3A4 (0.69) | SMN1; SMN2LMNACYP3A4ALDH1A1KDM4E | |
| SCHEMBL28343462 | 0.80 | CYP3A4 (0.69) | SMN1; SMN2LMNACYP3A4ALDH1A1KDM4E | |
| SCHEMBL8224505 | 0.80 | MEN1 (0.45) | LMNACYP3A4ALDH1A1TDP1TSHR | |
| Butylbenzyl SCHEMBL27854651 | 0.79 | LMNA (0.49) | NPC1RAB9ALMNACYP3A4ALDH1A1 | |
| Palmitic Acid SCHEMBL20485943 | 0.79 | TSHR (0.54) | LMNACYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL11306827 | 0.79 | CYP3A4 (0.67) | SMN1; SMN2LMNACYP3A4ALDH1A1KDM4E | |
| SCHEMBL1355708 | 0.79 | CYP3A4 (0.67) | SMN1; SMN2LMNACYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482347-B | modified antibody compositions and methods of making and using the same | 希托马克斯医疗有限责任公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-102482347-A | Modified antibody compositions and methods of making and using the same | CYTOMX THERAPEUTICS LLC | 2012-05-30 | — | — | CN | disclosed |