Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568085 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1091812 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTNPC1RAB9ATGM2 | |
| SCHEMBL13700872 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7126108 | 0.80 | PEPD (0.68) | ALDH1A1MAPTNPC1RAB9ANFKB1 | |
| Hydrochloric Acid SCHEMBL28052565 | 0.80 | ALDH1A1 (0.95) | ALDH1A1MAPTNPC1RAB9ATP53 | |
| SCHEMBL2200065 | 0.80 | PTPN1 (0.61) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12657665 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30890711 | 0.78 | MAPT (0.58) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11436685 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12597618 | 0.78 | KDM4E (0.68) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1826333-B | Diamine derivatives | DAIICHI SANKYO CO LTD | 2012-12-26 | — | — | CN | disclosed |
| CN-102002059-B | Process for producing thiazole derivative | DAIICHI SANKYO CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101914107-B | Process for producing thiazole derivative | DAIICHI SEIYAKU CO | 2012-03-07 | — | — | CN | disclosed |