SCHEMBL27857048

SCHEMBL27857048

CCCCCCCC/C=C\CCCCCCCCOC(=O)C(C)CN(C)C

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.49
EPHX2 P34913 2/20 0.45
CNR1 P21554 1/20 0.44
GMNN O75496 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
APEX1 P27695 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HSD17B10 Q99714 1/20 0.42
DUSP3 P51452 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9404488 0.84 FAAH (0.54) FAAHEPHX2GMNNUSP2LMNA
SCHEMBL6473634 0.84 FAAH (0.54) FAAHEPHX2GMNNUSP2LMNA
SCHEMBL6473641 0.84 FAAH (0.54) FAAHEPHX2GMNNUSP2LMNA
SCHEMBL9956940 0.83 FAAH (0.52) FAAHEPHX2GMNNUSP2LMNA
SCHEMBL29375743 0.83 FAAH (0.47) FAAHEPHX2CNR1MAPT
SCHEMBL11876622 0.82 FAAH (0.51) FAAHEPHX2GMNNUSP2LMNA
SCHEMBL11876641 0.82 FAAH (0.51) FAAHEPHX2GMNNUSP2LMNA
SCHEMBL8814234 0.81 FAAH (0.56) FAAHEPHX2GMNNUSP2LMNA
SCHEMBL8814218 0.81 FAAH (0.56) FAAHEPHX2GMNNUSP2LMNA
SCHEMBL6477854 0.81 FAAH (0.56) FAAHEPHX2GMNNUSP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110312799-A Novel C RISPR enzyme and system 博德研究所 2019-10-08 CN disclosed
CN-110114461-A NOVEL CRISPR ENZYMES AND SYSTEMS 博德研究所 2019-08-09 CN disclosed
CN-110003030-A Trialkyl cation lipid and its application method 野草莓树生物制药公司 2019-07-12 CN disclosed
CN-109563511-A Compositions and methods for delivering messenger RNA 阿布特斯生物制药公司 2019-04-02 CN disclosed
CN-107208095-A Composition and method for making hepatitis B virogene expression silencing 普洛体维生物治疗公司 2017-09-26 CN disclosed
CN-102245590-A Improved amino lipids and methods of delivering nucleic acids TEKMIRA PHARMACEUTICALS CORP 2011-11-16 CN disclosed