Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | ST6GAL1 | P15907 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xylose SCHEMBL27858293 | 0.93 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL2212574 | 0.88 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL79966 | 0.88 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10177274 | 0.88 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL4735554 | 0.88 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL3608348 | 0.88 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL18151989 | 0.88 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11617377 | 0.88 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| Cytarabine 5'-Phosphate SCHEMBL27855304 | 0.87 | P2RY2 (0.55) | LMNATHRBMTORMDM2NCOA1 | |
| Cytidine SCHEMBL21381483 | 0.87 | LMNA (0.72) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104857526-B | The method for treating eye disease | 夸克制药公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-102458418-B | Pharmaceutical application of oligonucleotide compound | QUARK PHARMACEUTICALS, INC. (US) | 2015-09-16 | — | — | CN | disclosed |
| CN-102458418-A | Method for treating chronic kidney disease | QUARK PHARMACEUTICALS INC | 2012-05-16 | — | — | CN | disclosed |
| CN-102026670-A | Novel siRNA compounds for inhibition of RTP801 | QUARK PHARMACEUTICALS INC | 2011-04-20 | — | — | CN | disclosed |