Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.72 |
| ▸ | PPARA | Q07869 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7705747 | 0.96 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL7921358 | 0.92 | PPARG (0.69) | PPARGPPARA | |
| SCHEMBL2786495 | 0.91 | PPARG (0.84) | PPARGPPARA | |
| SCHEMBL9281649 | 0.89 | PPARG (0.79) | PPARGPPARA | |
| SCHEMBL7705744 | 0.87 | PPARG (0.59) | PPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL7711576 | 0.87 | PPARG (0.78) | PPARGPPARA | |
| SCHEMBL9287578 | 0.87 | PPARG (0.78) | PPARGPPARA | |
| SCHEMBL9273453 | 0.87 | PPARG (0.83) | PPARGPPARA | |
| SCHEMBL6936735 | 0.86 | PPARG (0.82) | PPARGPPARA | |
| SCHEMBL6939250 | 0.85 | PPARG (0.81) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110300129-A1 | SYSTEMS AND METHODS FOR ENHANCING VACCINE EFFICACY | UNIVERSITY OF ROCHESTER (US) | 2011-12-08 | — | — | US | disclosed |
| WO-2010075037-A1 | SYSTEMS AND METHODS FOR ENHANCING VACCINE EFFICACY | UNIVERSITY OF ROCHESTER (US) | 2010-07-01 | — | — | WO | disclosed |