Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.69 |
| ▸ | PPARA | Q07869 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785850 | 0.92 | PPARG (0.72) | PPARGPPARA | |
| SCHEMBL7920689 | 0.90 | PPARG (0.77) | PPARGPPARA | |
| SCHEMBL7705744 | 0.89 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL9288468 | 0.88 | PPARG (0.76) | PPARGPPARA | |
| SCHEMBL9220466 | 0.88 | PPARG (0.76) | PPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL7705747 | 0.88 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL9285969 | 0.86 | PPARG (0.77) | PPARGPPARA | |
| SCHEMBL9222257 | 0.86 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL9215366 | 0.86 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL9276908 | 0.85 | PPARG (0.72) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888317-B1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LTD (GB) | 2001-09-12 | — | — | EP | disclosed |
| EP-0888317-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997031907-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1997-09-04 | — | — | WO | disclosed |