SCHEMBL27858563

SCHEMBL27858563

COC(=O)c1csc(-c2ccccc2S)c1.[Zn]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.42
▸ MAOA P21397 1/20 0.40
▸ ACHE P22303 1/20 0.40
▸ CDC25B P30305 2/20 0.38
▸ PTPRC P08575 1/20 0.38
▸ PTPRF P10586 1/20 0.38
▸ PTPN1 P18031 1/20 0.38
▸ CDC25A P30304 1/20 0.37
▸ CYP19A1 P11511 1/20 0.37
▸ ALDH1A1 P00352 3/20 0.37
▸ HPGD P15428 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ PRKCZ Q05513 1/20 0.37
▸ EGFR P00533 1/20 0.37
▸ PDK2 Q15119 2/20 0.36
▸ POLB P06746 1/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27875207 0.99 TSHR (0.43) TSHRMAOAACHECDC25BPTPRC
SCHEMBL27874977 0.97 TSHR (0.42) TSHRMAOAACHECDC25BPTPRC
SCHEMBL28795821 0.82 S100A4 (0.42) ALDH1A1HPGDMEN1KMT2APDK2
SCHEMBL27914304 0.81 MAPT (0.31) MAPT
SCHEMBL27858537 0.81 PARP1 (0.37) TSHRACHEALDH1A1HPGDMEN1
SCHEMBL27947355 0.81 TSHR (0.40) TSHRMAOAACHEALDH1A1HPGD
SCHEMBL27874978 0.79 PARP1 (0.38) TSHRACHEALDH1A1HPGDMEN1
SCHEMBL27914359 0.79 MAPT (0.32) PTPRCMAPT
SCHEMBL27914341 0.78 PARP1 (0.37) TSHRACHEALDH1A1HPGDMEN1
SCHEMBL27914329 0.78 MAPT (0.31) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105381573-B Golf 邓禄普体育用品株式会社 2018-03-09 — — CN disclosed
CN-103446724-B Golf 邓禄普体育用品株式会社 2018-01-19 — — CN disclosed
CN-103418115-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-05-11 — — CN disclosed
CN-103418116-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-05-04 — — CN disclosed
CN-103372285-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-04-20 — — CN disclosed
CN-105381573-A GOLF BALL DUNLOP SPORTS CO LTD 2016-03-09 — — CN disclosed
CN-103446722-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 — — CN disclosed
CN-103446721-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 — — CN disclosed
CN-103446723-B Golf DUNLOP SPORTS CO., LTD. (JP) 2015-11-18 — — CN disclosed
CN-102526997-B Golf ball DUNLOP SPORTS CO LTD 2015-04-15 — — CN disclosed
CN-103446724-A Golf ball DUNLOP SPORTS CO LTD 2013-12-18 — — CN disclosed
CN-103446722-A Golf ball DUNLOP SPORTS CO LTD 2013-12-18 — — CN disclosed
CN-103446720-A Golf ball DUNLOP SPORTS CO LTD 2013-12-18 — — CN disclosed
CN-103446723-A Golf ball DUNLOP SPORTS CO LTD 2013-12-18 — — CN disclosed
CN-103418116-A Golf ball DUNLOP SPORTS CO LTD 2013-12-04 — — CN disclosed
CN-103418115-A Golf ball DUNLOP SPORTS CO LTD 2013-12-04 — — CN disclosed
CN-103372285-A Golf ball DUNLOP SPORTS CO LTD 2013-10-30 — — CN disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 — — CN disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 — — CN disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 — — CN disclosed
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