Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27858793 | 0.89 | CYSLTR1 (0.41) | MAPTCYP2C9GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL27858794 | 0.81 | MAPT (0.50) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL3167208 | 0.74 | MAPT (0.56) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL27858791 | 0.72 | MAPT (0.45) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL27711658 | 0.71 | CTSA (0.41) | CYP2C19GRM2CTSAPDE10A | |
| SCHEMBL3166945 | 0.70 | GRM2 (0.54) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL6245068 | 0.67 | GRM2 (0.62) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL6244454 | 0.65 | GRM2 (0.60) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL27858800 | 0.65 | MAPT (0.60) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL9178096 | 0.65 | CYSLTR2 (0.58) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101061105-B | Potentiators of glutamate receptors | LILLY CO ELI | 2012-05-30 | — | — | CN | disclosed |