SCHEMBL278605

SCHEMBL278605

CCc1ccc2c(c1)[nH]c1cc(CC)ccc12

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.81
DAO P14920 1/20 0.46
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TRPA1 O75762 1/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
CDK2 P24941 2/20 0.41
CDK1 P06493 1/20 0.41
MAOA P21397 2/20 0.41
DYRK1A Q13627 2/20 0.41
HTR1A P08908 2/20 0.41
HTR1D P28221 2/20 0.41
HTR1B P28222 2/20 0.41
PTGES O14684 1/20 0.40
CYP2C9 P11712 1/20 0.40
AHR P35869 1/20 0.39
PTGS2 P35354 1/20 0.39
CCNE2 O96020 1/20 0.39
CDK4 P11802 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29864765 1.00 KIF11 (0.81) KIF11DAOKDM4EALDH1A1TRPA1
SCHEMBL278610 0.90 KIF11 (1.00) KIF11KDM4EALDH1A1AHR
SCHEMBL6009663 0.90 KIF11 (0.68) KIF11DAOKDM4EALDH1A1MAOA
SCHEMBL17226000 0.87 KIF11 (0.64) KIF11DAOKDM4EALDH1A1MAOA
SCHEMBL13560650 0.84 KIF11 (0.61) KIF11DAOKDM4EALDH1A1CDK2
SCHEMBL8004981 0.84 KIF11 (0.65) KIF11CYP1A2PTGS2
SCHEMBL6009064 0.82 KIF11 (0.58) KIF11KDM4EALDH1A1MAOADYRK1A
SCHEMBL22984494 0.81 KIF11 (0.58) KIF11DAOKDM4EALDH1A1CDK2
SCHEMBL30458204 0.81 KIF11 (0.62) KIF11DAOKDM4EALDH1A1TRPA1
SCHEMBL5494899 0.81 KIF11 (0.62) KIF11DAOKDM4EALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150502-A1 BIPHENYLPHENOL POLYMERIZATION CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-09 US disclosed
CN-116724062-A Biphenol polymerization catalyst 陶氏环球技术有限责任公司 2023-09-08 CN disclosed
US-8134143-B2 2,7-carbazolenevinylene derivatives as novel materials in producing organic based electronic devices NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2012-03-13 US disclosed
US-20070176163-A1 2,7-Carbazolenevinylene derivatives as novel materials in producing organic based electronic devices NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2007-08-02 US disclosed
US-20060183022-A1 Electrochemical cell NEC TOKIN CORORATION (JP) 2006-08-17 US disclosed