Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585808 | 1.00 | ACHE (0.49) | ACHEALDH1A1BACE1BCHECYP1A2 | |
| SCHEMBL586645 | 1.00 | ACHE (0.49) | ACHEALDH1A1BACE1BCHECYP1A2 | |
| SCHEMBL27862870 | 1.00 | ACHE (0.49) | ACHEALDH1A1BACE1BCHECYP1A2 | |
| SCHEMBL12459770 | 0.87 | ACHE (0.53) | ACHEALDH1A1BACE1BCHECYP1A2 | |
| SCHEMBL12459768 | 0.87 | ACHE (0.53) | ACHEALDH1A1BACE1BCHECYP1A2 | |
| SCHEMBL5980555 | 0.85 | ACHE (0.54) | ACHEALDH1A1BACE1BCHECYP1A2 | |
| SCHEMBL7779863 | 0.85 | ACHE (0.54) | ACHEALDH1A1BACE1BCHECYP1A2 | |
| SCHEMBL7775686 | 0.85 | ACHE (0.54) | ACHEALDH1A1BACE1BCHECYP1A2 | |
| SCHEMBL7775764 | 0.85 | ACHE (0.54) | ACHEALDH1A1BACE1BCHECYP1A2 | |
| SCHEMBL13676574 | 0.82 | ACHE (0.57) | ACHEALDH1A1BACE1BCHECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102388036-A | Serotonin and norepinephrine reuptake inhibitor | LILLY CO ELI | 2012-03-21 | — | — | CN | disclosed |