Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 17/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764042 | 0.87 | LRRK2 (0.49) | LRRK2 | |
| SCHEMBL3769228 | 0.84 | LRRK2 (0.49) | LRRK2 | |
| SCHEMBL3780407 | 0.81 | LRRK2 (0.51) | LRRK2 | |
| SCHEMBL19564547 | 0.79 | LRRK2 (0.53) | LRRK2 | |
| SCHEMBL3768568 | 0.78 | LRRK2 (0.52) | LRRK2 | |
| SCHEMBL3762010 | 0.78 | LRRK2 (0.60) | LRRK2 | |
| SCHEMBL3775929 | 0.78 | LRRK2 (0.60) | LRRK2 | |
| SCHEMBL382421 | 0.77 | LRRK2 (0.53) | LRRK2 | |
| SCHEMBL3762186 | 0.77 | LRRK2 (0.52) | LRRK2 | |
| SCHEMBL16864483 | 0.77 | LRRK2 (0.57) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102428084-A | Compounds | MEDICAL RES COUNCIL TECHNOLOGY | 2012-04-25 | — | — | CN | disclosed |