Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12812476 | 0.89 | MAPT (0.44) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1442150 | 0.88 | MAPT (0.46) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10179077 | 0.86 | NPC1 (0.58) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10179663 | 0.86 | MAPT (0.59) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1443036 | 0.85 | NPC1 (0.45) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1442956 | 0.84 | MAPT (0.61) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1441950 | 0.84 | CHEK1 (0.43) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1443575 | 0.83 | RAB9A (0.49) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1442658 | 0.83 | MAPT (0.43) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1442650 | 0.82 | HRH4 (0.56) | NPC1RAB9ASMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596932-A | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors | BAYER SCHERING PHARMA AG | 2012-07-18 | — | — | CN | claimed |