Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.40 |
| ▸ | ATR | Q13535 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27865671 | 0.93 | PKMYT1 (0.44) | PKMYT1HPGDPIK3CAPIK3CDPIK3CB | |
| SCHEMBL28799905 | 0.90 | CDC7 (0.43) | HPGDPIK3CAKDM4EALDH1A1GAA | |
| SCHEMBL27865706 | 0.88 | HPGD (0.43) | PKMYT1HPGDPIK3CAPIK3CDPIK3CB | |
| SCHEMBL27882150 | 0.83 | HPGD (0.41) | HPGDPIK3CAPIK3CDPIK3CBMTOR | |
| SCHEMBL27865694 | 0.83 | HPGD (0.41) | HPGDPIK3CAKDM4EALDH1A1GAA | |
| SCHEMBL1444098 | 0.80 | HPGD (0.53) | HPGDPIK3CAPIK3CDPIK3CBMTOR | |
| SCHEMBL27865711 | 0.78 | HPGD (0.43) | HPGDPIK3CAALDH1A1MKNK1MKNK2 | |
| SCHEMBL3091537 | 0.78 | PIK3CA (0.55) | HPGDPIK3CAPIK3CDPIK3CBMTOR | |
| SCHEMBL1443292 | 0.77 | CNR2 (0.53) | HPGDPIK3CAPIK3CDPIK3CBMTOR | |
| SCHEMBL1442345 | 0.77 | LRRK2 (0.51) | HPGDPIK3CAPIK3CDPIK3CBMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596932-A | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors | BAYER SCHERING PHARMA AG | 2012-07-18 | — | — | CN | claimed |