Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28799905 | 0.93 | CDC7 (0.43) | HPGDCDC7PIK3CAROCK2MAP4K4 | |
| SCHEMBL27865671 | 0.90 | PKMYT1 (0.44) | HPGDPIK3CAHCAR2ALDH1A1IKBKB | |
| SCHEMBL27865711 | 0.85 | HPGD (0.43) | HPGDCDC7PIK3CAROCK2MAP4K4 | |
| SCHEMBL27865719 | 0.83 | PKMYT1 (0.45) | HPGDPIK3CAHCAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28799885 | 0.82 | HPGD (0.40) | HPGDCDC7PIK3CAROCK2MAP4K4 | |
| SCHEMBL12812433 | 0.81 | HPGD (0.44) | HPGDCDC7PIK3CAROCK2MAP4K4 | |
| SCHEMBL1442287 | 0.80 | PTPN11 (0.47) | HPGDPIK3CAALDH1A1POLBALOX12 | |
| SCHEMBL1442584 | 0.78 | HPGD (0.58) | HPGDPIK3CAHCAR2MKNK1MKNK2 | |
| SCHEMBL27865706 | 0.77 | HPGD (0.43) | HPGDPIK3CAHCAR2ALDH1A1KDM4E | |
| SCHEMBL1442754 | 0.76 | PIK3CA (0.51) | HPGDPIK3CAALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596932-A | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors | BAYER SCHERING PHARMA AG | 2012-07-18 | — | — | CN | claimed |