Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848977 | 0.90 | CNR2 (0.40) | CNR2MMP7LMNAGAAACP3 | |
| SCHEMBL27848983 | 0.83 | CNR2 (0.41) | CNR2MMP7ACP3MAPK1POLB | |
| SCHEMBL10216817 | 0.83 | MC4R (0.41) | CNR2MMP7MC4RGAAACP3 | |
| Hydrochloric Acid SCHEMBL3446624 | 0.82 | MC4R (0.40) | CNR2MMP7MC4RGAAACP3 | |
| SCHEMBL2699407 | 0.80 | CNR2 (0.44) | CNR2MC4RACP3MAPK1POLB | |
| SCHEMBL3448694 | 0.79 | CNR2 (0.46) | CNR2MMP7MC4RACP3MAPK1 | |
| SCHEMBL28796970 | 0.78 | CNR2 (0.46) | CNR2LMNAGAAACP3MAPK1 | |
| SCHEMBL27848985 | 0.75 | EPHX1 (0.46) | MMP7POLBSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL382042 | 0.75 | CNR2 (0.40) | CNR2MMP7MC4RACP3POLB | |
| SCHEMBL6017225 | 0.75 | CYP1A2 (0.43) | CNR2ACP3MAPK1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102438990-A | Substituted 2-acetamido-5-aryl-1, 2, 4-triazolones and use thereof | BAYER SCHERING PHARMA AG | 2012-05-02 | — | — | CN | disclosed |