Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM5C | P41229 | 1/20 | 0.48 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 4/20 | 0.33 |
| ▸ | FEN1 | P39748 | 4/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221131 | 0.97 | EGLN1 (0.50) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL28034174 | 0.95 | EGLN1 (0.48) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL19423 | 0.83 | — | — | |
| SCHEMBL26967576 | 0.83 | KDM4E (0.55) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL10936077 | 0.83 | KDM4E (0.55) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL1171104 | 0.80 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| Water SCHEMBL7871948 | 0.80 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL221240 | 0.80 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL1245971 | 0.80 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL2927603 | 0.80 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102625846-A | Organisms for the production of 1, 3-butanediol | GENOMATICA INC | 2012-08-01 | — | — | CN | disclosed |