SCHEMBL27867136

SCHEMBL27867136

CCCCCCCc1nc(C)cn1C(C)N

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SPNS2 Q8IVW8 2/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
KCNH2 Q12809 1/20 0.35
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TLR7 Q9NYK1 1/20 0.34
HTR2A P28223 1/20 0.33
SPHK1 Q9NYA1 4/20 0.33
PDE10A Q9Y233 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27850124 1.00 SPNS2 (0.36) SPNS2LMNATSHRKCNH2ATM
SCHEMBL27850149 1.00 SPNS2 (0.36) SPNS2LMNATSHRKCNH2ATM
SCHEMBL27867119 1.00 SPNS2 (0.36) SPNS2LMNATSHRKCNH2ATM
SCHEMBL27867144 1.00 SPNS2 (0.36) SPNS2LMNATSHRKCNH2ATM
SCHEMBL27867129 1.00 SPNS2 (0.36) SPNS2LMNATSHRKCNH2ATM
SCHEMBL27850136 0.94 NOS2 (0.33) SPNS2ATMSMN1; SMN2TLR7
SCHEMBL27850101 0.86 SPNS2 (0.36) SPNS2LMNATSHRKCNH2ATM
SCHEMBL27850109 0.86 SPNS2 (0.36) SPNS2LMNATSHRKCNH2ATM
SCHEMBL27867115 0.86 SPNS2 (0.36) SPNS2LMNATSHRKCNH2ATM
SCHEMBL27850157 0.86 SPNS2 (0.36) SPNS2LMNATSHRKCNH2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102414241-A Microencapsulated composition containing imidazole compound, curable composition using same, and masterbatch-type curing agent ASAHI KASEI E MATERIALS CORP 2012-04-11 CN disclosed