SCHEMBL278674

SCHEMBL278674

O=C=Nc1ccc(-c2ccc(N=C=O)c(-c3ccccc3)c2)cc1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.53
ALDH1A1 P00352 2/20 0.53
HPGD P15428 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
MEN1 O00255 2/20 0.40
NPC1 O15118 2/20 0.40
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
APAF1 O14727 1/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.40
XBP1 P17861 1/20 0.40
PTBP1 P26599 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28472322 0.85 CYP3A4 (0.41) CYP3A4ALDH1A1HPGDTDP1MEN1
SCHEMBL2807367 0.85 CYP3A4 (0.49) CYP3A4ALDH1A1HPGDTDP1CASP3
SCHEMBL28472321 0.84 CYP3A4 (0.40) CYP3A4ALDH1A1HPGDTDP1MEN1
SCHEMBL17847481 0.84 CYP3A4 (0.38) CYP3A4ALDH1A1HPGDTDP1CASP3
SCHEMBL17847479 0.84 CYP3A4 (0.44) CYP3A4ALDH1A1HPGDTDP1MEN1
SCHEMBL11613362 0.84 PTGDR2 (0.42) CYP3A4ALDH1A1HPGDTDP1MEN1
SCHEMBL17847449 0.84 CYP3A4 (0.38) CYP3A4ALDH1A1HPGDTDP1MEN1
SCHEMBL15822503 0.84 PTGDR2 (0.42) CYP3A4ALDH1A1HPGDTDP1MAPT
SCHEMBL11022515 0.83 CYP3A4 (0.51) CYP3A4ALDH1A1HPGDTDP1TRPA1
SCHEMBL27620107 0.82 CYP3A4 (0.50) CYP3A4ALDH1A1HPGDTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 488 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3094661-B1 COMPOSITIONS WITH ENHANCED FLEXIBILITY MOMENTIVE PERFORMANCE MAT INC (US) 2019-06-19 EP claimed
US-9890303-B2 Compositions with enhanced flexibility MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-02-13 US claimed
US-20170283544-A1 COMPOSITIONS WITH ENHANCED FLEXIBILITY MOMENTIVE PERFORMANCE MATERIALS INC. 2017-10-05 US claimed
US-9718995-B2 Compositions with enhanced flexibility MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-08-01 US claimed
EP-3094661-A1 COMPOSITIONS WITH ENHANCED FLEXIBILITY Momentive Performance Materials Inc. (US) 2016-11-23 EP claimed
US-20150203724-A1 COMPOSITIONS WITH ENHANCED FLEXIBILITY MOMENTIVE PERFORMANCE MATERIALS INC. 2015-07-23 US claimed
WO-2015108905-A1 COMPOSITIONS WITH ENHANCED FLEXIBILITY MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-07-23 WO claimed
EP-1669385-B1 Continuous method for manufacturing an acid functional blocked solid isocyanate BAYER MATERIALSCIENCE LLC (US) 2011-05-04 EP claimed
EP-1654306-A4 WATER-BASED POLYURETHANE - POLYETHYLENE COMPOSITIONS VALSPAR SOURCING INC (US) 2008-05-07 EP claimed
EP-1915411-A1 NEW ORGANIC BOTTOM ANTIREFLECTIVE POLYMER COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2008-04-30 EP claimed
US-20070027249-A1 Water-based polyurethane-polyethylene compositions VALSPAR SOURCING, INC. (US) 2007-02-01 US claimed
US-20070020557-A1 New organic bottom antireflective polymer compositions AZ ELECTRONIC MATERIALS USA CORP. 2007-01-25 US claimed
WO-2007010385-A1 NEW ORGANIC BOTTOM ANTIREFLECTIVE POLYMER COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2007-01-25 WO claimed
EP-1669385-A1 Continuous method for manufacturing an acid functional blocked solid isocyanate Bayer MaterialScience LLC (US) 2006-06-14 EP claimed
US-20060122357-A1 Continuous method for manufacturing an acid functional blocked solid isocyanate BAYER MATERIALSCIENCE LLC 2006-06-08 US claimed
EP-1654306-A1 WATER-BASED POLYURETHANE - POLYETHYLENE COMPOSITIONS THE VALSPAR CORPORATION (US) 2006-05-10 EP claimed
WO-2005016999-A1 WATER-BASED POLYURETHANE - POLYETHYLENE COMPOSITIONS THE VALSPAR CORPORATION (US) 2005-02-24 WO claimed
EP-0153456-B1 CHEMICALLY HARDENABLE TWO-COMPONENT POLYURETHANE PREPOLYMER COMPOSITION, PROCESS FOR PREPARING A POLYURETHANE, AND USE OF THE TWO-COMPONENT COMPOSITION Gurit-Essex AG (CH) 1988-06-15 EP claimed
US-4672100-A SELF-SEALING GURIT-ESSEX AG (CH) 1987-06-09 US claimed
US-4178277-A Modified polyesters DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-12-11 US claimed