SCHEMBL2807367

SCHEMBL2807367

O=C=Nc1ccc(N=C=O)c(-c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.49
TRPA1 O75762 1/20 0.49
TDP1 Q9NUW8 2/20 0.43
MAPK1 P28482 1/20 0.43
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
TSHR P16473 1/20 0.37
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
BACE1 P56817 1/20 0.33
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
CYP1A2 P05177 1/20 0.32
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5171045 0.86 CYP3A4 (0.53) CYP3A4TRPA1TDP1MAPK1ALDH1A1
SCHEMBL278674 0.85 CYP3A4 (0.53) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL7061343 0.85 MAPK1 (0.46) CYP3A4TRPA1TDP1MAPK1CASP3
Hydrogen Sulfide SCHEMBL21797064 0.84 CYP3A4 (0.51) CYP3A4TRPA1TDP1MAPK1ALDH1A1
SCHEMBL14688874 0.82 MAPK1 (0.43) CYP3A4TRPA1TDP1MAPK1CASP3
SCHEMBL9229680 0.82 MAPK1 (0.43) CYP3A4TRPA1TDP1MAPK1CASP3
SCHEMBL17847479 0.81 CYP3A4 (0.44) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL15822503 0.81 PTGDR2 (0.42) CYP3A4TDP1MAPK1ALDH1A1HPGD
SCHEMBL17847449 0.81 CYP3A4 (0.38) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL11613362 0.81 PTGDR2 (0.42) CYP3A4TDP1MAPK1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
CN-101550236-B Synthesis of polyimides (pi) from poly-carbodiimides and dianhydrides by sequential self-repetitive reaction (ssrr) DADONG RESIN CHEMICALS CO LTD 2011-09-14 CN claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-101550236-A Synthesis of polyimides (PI) from poly-carbodiimides and dianhydrides by sequential self-repetitive reaction (SSRR) GREAT EASTERN RESINS IND CO LT (CN) 2009-10-07 CN claimed
CN-101092547-A Special adhesive for liquid pesticide bag ADHESIVE FACTORY JINTAN CITY (CN) 2007-12-26 CN claimed
CN-118325563-A Double-component polyurethane binder and preparation method and application thereof 恒基能脉新能源科技有限公司 2024-07-12 CN disclosed
CN-114851452-B GPU sole full-automatic pouring molding device and preparation method 茂泰(福建)新材料科技有限公司 2024-05-24 CN disclosed
CN-116836619-A Preparation method of polyurethane building coating 华东理工大学 2023-10-03 CN disclosed
CN-113661190-B Laminated component comprising an anti-slip and waterproof outer layer and method for the production thereof 科思创有限公司 2023-08-01 CN disclosed
US-9561165-B2 Cosmetic treatment processes and kit L'OREAL (FR) 2017-02-07 US disclosed
CN-105637416-A Method for making photochromic optical articles using organic solvent pretreatment and photochromic coatings TRANSITIONS OPTICAL INC 2016-06-01 CN disclosed
US-20160051458-A1 COSMETIC TREATMENT PROCESSES AND KIT OREAL (FR) 2016-02-25 US disclosed
EP-0783728-B1 RADIATION-SENSITIVE ADDUCTS COMPRISING DIAZONIUM CATIONS, QUATERNARY CATIONS, AND SULFONATED POLYESTER ANIONS MINNESOTA MINING & MFG (US) 1999-12-08 EP disclosed
EP-0783728-A1 RADIATION-SENSITIVE ADDUCTS COMPRISING DIAZONIUM CATIONS, QUATERNARY CATIONS, AND SULFONATED POLYESTER ANIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-16 EP disclosed
US-5583230-A Polymerizable compound having mildew resistance and polymer thereof TOYO BOSEKI KABUSHIKI KAISHA (JP) 1996-12-10 US disclosed
US-5527655-A FOR COATING LITHOGRAPHIC PLATES; QUATERNARY AMMONIUM AND PHOSPHONIUM SALTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-18 US disclosed
WO-1996010217-A1 RADIATION-SENSITIVE ADDUCTS COMPRISING DIAZONIUM CATIONS, QUATERNARY CATIONS, AND SULFONATED POLYESTER ANIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-04 WO disclosed
US-5460892-A Polyester oligomer/polyacrylate where polyacrylate contains hydrophilic and hydrophobic portion and polyester contains hydroxyl functions, capped polyisocyanates are also included in coating material Herberts Gessellschaft mit beschrankter Haftung (DE) 1995-10-24 US disclosed
US-4956431-A FUNGICIDES TOYO BOSEKI KABUSHIKI KAISHA (JP) 1990-09-11 US disclosed
US-4322327-A Slow-curing water-curable urethane prepolymer composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1982-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 CYP3A4 4568/4885TRPA1 806/4885TDP1 3475/4885
US-20160051458-A1 COSMETIC TREATMENT PROCESSES AND KIT KIT, KRT18, MKI67 CYP3A4 4389/4885TRPA1 866/4885TDP1 1675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.