Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.39 |
| ▸ | PPARA | Q07869 | 8/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27867749 | 0.89 | PPARG (0.38) | PPARGPPARAPPARDRORC | |
| SCHEMBL28800055 | 0.87 | PPARG (0.40) | PPARGPPARAPPARDRORC | |
| SCHEMBL27884208 | 0.86 | PPARG (0.39) | PPARGPPARAPPARDRORC | |
| SCHEMBL27867762 | 0.86 | PPARG (0.41) | PPARGPPARAPPARDRORC | |
| SCHEMBL12096763 | 0.85 | PPARG (0.54) | PPARGPPARAPPARDRORC | |
| SCHEMBL28800053 | 0.85 | PPARG (0.40) | PPARGPPARAPPARDRORC | |
| SCHEMBL27867730 | 0.85 | PPARG (0.41) | PPARGPPARAPPARDRORC | |
| SCHEMBL27867794 | 0.85 | PPARG (0.39) | PPARGPPARAPPARDRORC | |
| SCHEMBL28800079 | 0.83 | PPARG (0.36) | PPARGPPARAPPARDRORC | |
| SCHEMBL27936046 | 0.82 | PPARG (0.37) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596906-A | Use of indole derivatives as NURR-1 activators as agents for the treatment of Parkinson's disease | FOURNIER LAB SA | 2012-07-18 | — | — | CN | claimed |
| CN-102596906-A | Use of indole derivatives as NURR-1 activators as agents for the treatment of Parkinson's disease | FOURNIER LAB SA | 2012-07-18 | — | — | CN | disclosed |