Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | RORC | P51449 | 8/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27867794 | 0.92 | PPARG (0.39) | PPARGPPARAPPARDRORCCPT2 | |
| SCHEMBL28800055 | 0.90 | PPARG (0.40) | PPARGPPARAPPARDRORCCCR2 | |
| SCHEMBL27884208 | 0.88 | PPARG (0.39) | PPARGPPARAPPARDRORCCCR2 | |
| SCHEMBL27867749 | 0.86 | PPARG (0.38) | PPARGPPARAPPARDRORC | |
| SCHEMBL12096869 | 0.86 | PPARG (0.56) | PPARGPPARAPPARDRORCCCR2 | |
| SCHEMBL27867748 | 0.85 | PPARG (0.39) | PPARGPPARAPPARDRORC | |
| SCHEMBL27867762 | 0.85 | PPARG (0.41) | PPARGPPARAPPARDRORCKCNH2 | |
| SCHEMBL27867734 | 0.84 | CCR2 (0.39) | PPARGPPARAPPARDRORCCCR2 | |
| SCHEMBL28800053 | 0.84 | PPARG (0.40) | PPARGPPARAPPARDRORC | |
| SCHEMBL28807364 | 0.83 | PPARG (0.38) | PPARGPPARAPPARDRORCCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596906-A | Use of indole derivatives as NURR-1 activators as agents for the treatment of Parkinson's disease | FOURNIER LAB SA | 2012-07-18 | — | — | CN | disclosed |