Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904579 | 0.82 | TDP1 (0.55) | POLBMAPK1HDAC2TP53 | |
| SCHEMBL3765312 | 0.79 | TP53 (0.67) | MMP2MMP9MMP8POLBMAPK1 | |
| SCHEMBL31657792 | 0.76 | POLB (0.73) | MMP2MMP9MMP8POLBMAPK1 | |
| SCHEMBL5944038 | 0.76 | MAPT (0.60) | MMP2MMP9MMP8MAPK1 | |
| SCHEMBL7838339 | 0.75 | LMNA (0.64) | POLBMAPK1HDAC2 | |
| SCHEMBL27889371 | 0.75 | TSHR (0.68) | MMP2MMP9MMP8POLBMAPK1 | |
| SCHEMBL11756699 | 0.75 | FFAR1 (0.62) | MMP2MMP9MMP8POLBMAPK1 | |
| SCHEMBL29441683 | 0.74 | PLG (0.59) | MMP2MMP9MMP8POLBHDAC2 | |
| SCHEMBL3913268 | 0.74 | PLG (0.59) | MMP2MMP9MMP8POLBHDAC2 | |
| 4-Nitrobenzoic Acid SCHEMBL28737108 | 0.74 | TDP1 (0.66) | POLBMAPK1HDAC2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459231-A | Quaternary ammonium salt compound | TEIJIN PHARMA LTD | 2012-05-16 | — | — | CN | disclosed |