Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GPR3 | P46089 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374932 | 0.89 | GPR3 (0.68) | KDM4EGPR3MAPTALDH1A1RAB9A | |
| SCHEMBL9160474 | 0.89 | GPR3 (0.68) | KDM4EGPR3MAPTALDH1A1RAB9A | |
| SCHEMBL36332 | 0.89 | GPR3 (0.68) | KDM4EGPR3MAPTALDH1A1RAB9A | |
| SCHEMBL10476774 | 0.89 | GPR3 (0.68) | KDM4EGPR3MAPTALDH1A1RAB9A | |
| SCHEMBL30515127 | 0.89 | GPR3 (0.68) | KDM4EGPR3MAPTALDH1A1RAB9A | |
| Sulfuric Acid SCHEMBL25287839 | 0.87 | KDM4E (0.56) | KDM4EGPR3MAPTALDH1A1RAB9A | |
| Hydroxyamine SCHEMBL28987533 | 0.86 | KDM4E (0.60) | KDM4EGPR3MAPTALDH1A1RAB9A | |
| Ammonia Solution, Strong SCHEMBL1871981 | 0.86 | GPR3 (0.65) | KDM4EGPR3MAPTALDH1A1RAB9A | |
| Ethylene SCHEMBL9721424 | 0.86 | GPR3 (0.65) | KDM4EGPR3MAPTALDH1A1RAB9A | |
| Water SCHEMBL8091139 | 0.86 | GPR3 (0.65) | KDM4EGPR3MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102740699-A | Mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction | UNIV VANDERBILT | 2012-10-17 | — | — | CN | disclosed |
| CN-102665417-A | Mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction | UNIV VANDERBILT | 2012-09-12 | — | — | CN | disclosed |
| CN-102665411-A | MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction | UNIV VANDERBILT | 2012-09-12 | — | — | CN | disclosed |