Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 16/20 | 0.84 |
| ▸ | ADAM33 | Q9BZ11 | 3/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997157 | 1.00 | ADAM17 (0.84) | ADAM17ADAM33MMP1MMP3ADAM10 | |
| SCHEMBL27853845 | 0.93 | ADAM17 (0.82) | ADAM17ADAM33MMP1MMP3 | |
| SCHEMBL27977404 | 0.93 | ADAM17 (0.82) | ADAM17ADAM33MMP1MMP3 | |
| SCHEMBL14244510 | 0.92 | ADAM17 (1.00) | ADAM17ADAM33MMP1MMP3ADAM10 | |
| SCHEMBL27853804 | 0.92 | ADAM17 (1.00) | ADAM17ADAM33MMP1MMP3ADAM10 | |
| SCHEMBL2682037 | 0.88 | ADAM17 (0.66) | ADAM17ADAM33MMP1MMP3 | |
| SCHEMBL997829 | 0.88 | ADAM17 (0.66) | ADAM17ADAM33MMP1MMP3 | |
| SCHEMBL995164 | 0.87 | ADAM17 (0.69) | ADAM17ADAM33MMP1MMP3 | |
| SCHEMBL995162 | 0.87 | ADAM17 (0.69) | ADAM17ADAM33MMP1MMP3 | |
| SCHEMBL996063 | 0.87 | ADAM17 (0.69) | ADAM17ADAM33MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471260-B | Novel benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-10-22 | — | — | CN | disclosed |
| CN-102471260-A | Novel benzenesulfonamide compounds, process for their synthesis and their use in pharmaceuticals and cosmetics | GALDERMA RES & DEV | 2012-05-23 | — | — | CN | disclosed |