Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28275392 | 0.98 | CYP3A4 (0.47) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL28166197 | 0.89 | CYP3A4 (0.49) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL6248707 | 0.86 | ALDH1A1 (0.50) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL5404290 | 0.85 | ALDH1A1 (0.50) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL3387314 | 0.85 | CYP3A4 (0.41) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL28045289 | 0.84 | CYP3A4 (0.54) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL7213996 | 0.83 | ALDH1A1 (0.57) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL4534402 | 0.81 | TSHR (0.47) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL8217861 | 0.80 | ALDH1A1 (0.52) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL23901155 | 0.80 | ALDH1A1 (0.43) | CYP3A4TSHRTDP1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102477159-B | Amino modified silicone oil and preparation method thereof | CHINA NAT BLUESTAR GROUP CO | 2013-09-04 | — | — | CN | disclosed |
| CN-102477159-A | Amino modified silicone oil and preparation method thereof | CHINA NAT BLUESTAR GROUP CO | 2012-05-30 | — | — | CN | disclosed |