Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ESRRG | P62508 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825883 | 1.00 | HDAC2 (0.33) | HDAC2DPP4ESRRG | |
| SCHEMBL27763280 | 0.86 | HDAC2 (0.33) | HDAC2DPP4 | |
| SCHEMBL27987362 | 0.86 | HDAC2 (0.33) | HDAC2DPP4 | |
| SCHEMBL27926697 | 0.86 | DRD2 (0.38) | HDAC2 | |
| SCHEMBL27926715 | 0.86 | DRD2 (0.38) | HDAC2 | |
| SCHEMBL27926781 | 0.86 | DRD2 (0.38) | HDAC2 | |
| SCHEMBL28055957 | 0.85 | HDAC2 (0.36) | HDAC2DPP4 | |
| SCHEMBL27870981 | 0.84 | SLC18A3 (0.33) | HDAC2 | |
| SCHEMBL27937100 | 0.83 | HDAC2 (0.33) | HDAC2 | |
| SCHEMBL27887192 | 0.81 | ELANE (0.31) | HDAC2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254623-A | SUBSTITUTED BENZAMIDES | HOFFMANN LA ROCHE | 2016-01-20 | — | — | CN | disclosed |
| CN-104837835-A | VEGFR3 inhibitors | CANCER THERAPEUTICS CRC PTY LTD | 2015-08-12 | — | — | CN | disclosed |
| CN-104684906-A | NAMPT inhibitors | ABBVIE INC | 2015-06-03 | — | — | CN | disclosed |
| CN-104619700-A | Pyrazole carboxamide derivatives as TAAR modulators for the treatment of several diseases, such as depression, diabetes and Parkinson's disease | HOFFMANN LA ROCHE | 2015-05-13 | — | — | CN | disclosed |
| CN-104603129-A | Triazole carboxamide derivatives | HOFFMANN LA ROCHE | 2015-05-06 | — | — | CN | disclosed |
| CN-104428301-A | NAMPT inhibitors | ABBVIE INC | 2015-03-18 | — | — | CN | disclosed |
| CN-103596937-A | Substituted benzamide derivatives | HOFFMANN LA ROCHE | 2014-02-19 | — | — | CN | disclosed |
| CN-103443074-A | Heterocyclic amine derivatives | HOFFMANN LA ROCHE | 2013-12-11 | — | — | CN | disclosed |
| CN-102686563-A | Substituted benzamide derivatives | HOFFMANN LA ROCHE | 2012-09-19 | — | — | CN | disclosed |