Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 4/20 | 0.66 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.41 |
| ▸ | IKBKB | O14920 | 4/20 | 0.38 |
| ▸ | CHUK | O15111 | 4/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | PRKACA | P17612 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28129959 | 0.82 | PRKCI (0.64) | PRKCIAXLNUDT1IKBKBCHUK | |
| SCHEMBL29431169 | 0.81 | PRKCI (1.00) | PRKCIAXLNUDT1IKBKBCHUK | |
| SCHEMBL99690 | 0.81 | PRKCI (1.00) | PRKCIAXLNUDT1IKBKBCHUK | |
| Tert-Butyl Formate SCHEMBL28804920 | 0.75 | PRKCI (0.35) | PRKCIDYRK1ATDP1 | |
| Tert-Butyl Formate SCHEMBL28046344 | 0.75 | PRKCI (0.43) | PRKCIAXLNUDT1CIT | |
| Tert-Butyl Formate SCHEMBL28092266 | 0.75 | AKT2 (0.51) | NUDT1ROCK1ROCK2GSK3B | |
| Tert-Butyl Formate SCHEMBL28046308 | 0.74 | PRKCI (0.44) | PRKCIAXLNUDT1AURKBJAK3 | |
| Tert-Butyl Formate SCHEMBL27893619 | 0.74 | AXL (0.64) | AXLNUDT1JAK2AURKBPRKACA | |
| Tert-Butyl Formate SCHEMBL27708218 | 0.74 | AHR (0.64) | AXLTDP1 | |
| Tert-Butyl Formate SCHEMBL28029826 | 0.71 | TDP1 (0.37) | PRKCIAXLJAK2TDP1JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117213-A | Heteroaryl compound and synthesis thereof and purification process | 西格诺药品有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-102686225-A | Process for synthesis and purification of heteroaryl compounds | SIGNAL PHARM LLC | 2012-09-19 | — | — | CN | disclosed |