Tert-Butyl Formate

Tert-Butyl Formate

SCHEMBL28046344

CC(C)(C)OC=O.c1cn(-c2ccnc3[nH]ccc23)nn1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 4/20 0.43
AKT2 P31751 2/20 0.38
NUDT1 P36639 5/20 0.36
PBK Q96KB5 2/20 0.35
EGLN2 Q96KS0 3/20 0.35
TET2 Q6N021 1/20 0.35
OGFOD1 Q8N543 1/20 0.35
TET1 Q8NFU7 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
HIF1AN Q9NWT6 1/20 0.35
OPRM1 P35372 1/20 0.35
OPRL1 P41146 1/20 0.35
AXL P30530 1/20 0.35
CIT O14578 1/20 0.34
ATR Q13535 1/20 0.34
ATRIP Q8WXE1 1/20 0.34
CCNK O75909 1/20 0.33
CDK12 Q9NYV4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28824874 0.85 PRKCI (0.55) PRKCIAKT2NUDT1PBKAXL
Tert-Butyl Formate SCHEMBL28046308 0.81 PRKCI (0.44) PRKCIAKT2NUDT1PBKOPRM1
Tert-Butyl Formate SCHEMBL28092266 0.77 AKT2 (0.51) AKT2NUDT1PBK
Tert-Butyl Formate SCHEMBL27893624 0.76 PRKCI (0.32) PRKCIEGLN2
Tert-Butyl Formate SCHEMBL27870995 0.75 PRKCI (0.66) PRKCINUDT1AXLCIT
SCHEMBL13774669 0.66 PRKCI (0.52) PRKCIAKT2NUDT1PBKAXL
Tert-Butyl Formate SCHEMBL27893619 0.66 AXL (0.64) NUDT1AXL
SCHEMBL21975051 0.66 PRKCI (0.49) PRKCIAKT2NUDT1PBKOPRM1
Tert-Butyl Formate SCHEMBL28029826 0.64 TDP1 (0.37) PRKCIAXLATR
SCHEMBL4934159 0.64 JAK1 (0.53) AKT2NUDT1PBK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102958918-B Novel tobacco amide derivatives or its salt FUJIFILM CORP. (JP) 2015-12-09 CN disclosed