Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.55 |
| ▸ | TP53 | P04637 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783672 | 0.88 | TP53 (0.48) | EPHX2TP53SMN1; SMN2MAPTKIT | |
| SCHEMBL2787195 | 0.87 | TP53 (0.63) | EPHX2TP53SMN1; SMN2MAPTFAAH | |
| SCHEMBL2785316 | 0.86 | TP53 (0.52) | EPHX2TP53SMN1; SMN2MAPTFAAH | |
| SCHEMBL2784409 | 0.84 | EPHX2 (0.46) | EPHX2MAPT | |
| SCHEMBL2785329 | 0.81 | HIF1A (0.53) | EPHX2TP53SMN1; SMN2MAPTFAAH | |
| SCHEMBL2784837 | 0.81 | EPHX2 (0.52) | EPHX2TP53SMN1; SMN2MAPTKIT | |
| SCHEMBL2786425 | 0.81 | HIF1A (0.46) | EPHX2TP53SMN1; SMN2MAPTPOLB | |
| SCHEMBL2787670 | 0.79 | TP53 (0.50) | TP53SMN1; SMN2MAPTFAAH | |
| SCHEMBL2784847 | 0.79 | HCRTR1 (0.43) | EPHX2TP53SMN1; SMN2MAPT | |
| SCHEMBL2784404 | 0.78 | TP53 (0.55) | EPHX2TP53SMN1; SMN2MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881967-B1 | SUBSTITUTED BENZO(D)ISOXAZOL-3-YL AMINE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2010-04-28 | — | — | EP | claimed |