Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2619230 | 0.76 | CYP2D6 (0.70) | SMN1; SMN2CYP2D6LMNANPSR1MEN1 | |
| SCHEMBL17627572 | 0.73 | CYP2D6 (0.51) | SMN1; SMN2CYP2D6LMNANPSR1MEN1 | |
| SCHEMBL357967 | 0.73 | CYP2D6 (0.51) | SMN1; SMN2CYP2D6LMNANPSR1MEN1 | |
| SCHEMBL2485840 | 0.73 | CYP2D6 (0.51) | SMN1; SMN2CYP2D6LMNANPSR1MEN1 | |
| SCHEMBL20374161 | 0.72 | CYP2D6 (0.50) | SMN1; SMN2CYP2D6LMNANPSR1MEN1 | |
| SCHEMBL4778694 | 0.69 | LMNA (0.50) | SMN1; SMN2CYP2D6LMNANPSR1MEN1 | |
| SCHEMBL20840303 | 0.69 | LMNA (0.50) | SMN1; SMN2CYP2D6LMNANPSR1MEN1 | |
| SCHEMBL737197 | 0.69 | — | — | |
| SCHEMBL2260774 | 0.69 | CYP2D6 (0.44) | SMN1; SMN2CYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL1024203 | 0.69 | CYP2D6 (0.44) | SMN1; SMN2CYP2D6MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482236-A | Indanone derivatives and pharmaceutical compositions containing the same | KOREA RES INST CHEM TECH | 2012-05-30 | — | — | CN | disclosed |