SCHEMBL2787203

SCHEMBL2787203

COc1c(C=O)cccc1C=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.73
CA2 P00918 1/20 0.73
ERN1 O75460 3/20 0.55
TLR2 O60603 1/20 0.55
TLR1 Q15399 1/20 0.55
TLR6 Q9Y2C9 1/20 0.55
SRC P12931 1/20 0.55
LMNA P02545 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
KMT2A Q03164 1/20 0.50
MCL1 Q07820 1/20 0.48
ALDH1A1 P00352 5/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
TSHR P16473 2/20 0.46
NFE2L2 Q16236 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3421185 0.89 CA1 (0.72) CA1CA2ERN1TLR2TLR1
SCHEMBL8598035 0.89 CA1 (0.61) CA1CA2ERN1TLR2TLR1
SCHEMBL23108166 0.87 CA1 (0.63) CA1CA2ERN1TLR2TLR1
O-Veratraldehyde SCHEMBL29923149 0.87 SRC (0.67) CA1CA2ERN1TLR2TLR1
O-Veratraldehyde SCHEMBL319070 0.87 SRC (0.67) CA1CA2ERN1TLR2TLR1
SCHEMBL1597634 0.87 CA1 (0.63) CA1CA2ERN1TLR2TLR1
SCHEMBL1709967 0.85 CA1 (0.61) CA1CA2ERN1TLR2TLR1
SCHEMBL9212970 0.85 CA1 (0.61) CA1CA2ERN1TLR2TLR1
SCHEMBL29951270 0.85 CA1 (0.61) CA1CA2ERN1TLR2TLR1
SCHEMBL680844 0.85 CA1 (0.61) CA1CA2ERN1TLR2TLR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240166867-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-05-23 US disclosed
EP-4286448-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-06 EP disclosed
CN-116940559-A Cyclic diol compound, process for producing the compound, and use of the compound 新日本理化株式会社 2023-10-24 CN disclosed
CN-116829618-A Thermoplastic resin and optical lens comprising the same 三菱瓦斯化学株式会社 2023-09-29 CN disclosed
WO-2023072786-A1 BIO-BASED AMINE CURING AGENT FOR CURABLE COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2023-05-04 WO disclosed
WO-2022163674-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME 三菱瓦斯化学株式会社 2022-08-04 WO disclosed
WO-2022163684-A1 CYCLIC DIOL COMPOUND, METHOD FOR PRODUCING SAID COMPOUND, AND USE OF SAID COMPOUND 新日本理化株式会社 2022-08-04 WO disclosed
US-8273678-B2 Highly active catalysts for alkylene oxide polymerization DOW GLOBAL TECHNOLOGIES LLC (US) 2012-09-25 US disclosed
EP-2423201-A1 Luminescent macrocyclic lanthanide complexes The Regents of The University of California (US) 2012-02-29 EP disclosed
EP-2152778-B1 HIGHLY ACTIVE CATALYSTS FOR ALKYLENE OXIDE POLYMERIZATION DOW GLOBAL TECHNOLOGIES INC (US) 2010-09-22 EP disclosed
US-20100197873-A1 HIGHLY ACTIVE CATALYSTS FOR ALKYLENE OXIDE POLYMERIZATION DDP SPECIALTY ELECTRONIC MATERIALS US, LLC. 2010-08-05 US disclosed
EP-2152778-A1 HIGHLY ACTIVE CATALYSTS FOR ALKYLENE OXIDE POLYMERIZATION Dow Global Technologies Inc. (US) 2010-02-17 EP disclosed
WO-2008134118-A1 HIGHLY ACTIVE CATALYSTS FOR ALKYLENE OXIDE POLYMERIZATION DOW GLOBAL TECHNOLOGIES INC. (US) 2008-11-06 WO disclosed
US-4962203-A ANTIASTHMATIC, ANTIALLERGENIC, ANTIINFLAMMATORY AND CYTOPROTECTIVE AGENTS MERCK FROST CANADA, INC. (CA) 1990-10-09 US disclosed
EP-0206751-A2 2-Substituted quinolines, their preparation and use MERCK FROSST CANADA INC. (CA) 1986-12-30 EP disclosed
US-4243783-A Fluoroaliphaticsulfonyl substituted ethylenes catalysts in polymerization processes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-01-06 US disclosed
US-4156696-A Fluoroaliphaticsulfonyl substituted methanes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-05-29 US disclosed
US-4069233-A Fluoroaliphaticsulfonyl substituted ethylenes substituted by furyl, thenyl, or 1H-pyrrolyl groups MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-01-17 US disclosed
US-3984357-A Fluoroaliphaticsulfonyl substituted ethylenes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-10-05 US disclosed
US-3932526-A Fluoroaliphaticsulfonyl substituted ethylenes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-01-13 US disclosed