Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | ERN1 | O75460 | 13/20 | 0.67 |
| ▸ | TLR2 | O60603 | 1/20 | 0.67 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.67 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.67 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787203 | 0.89 | CA1 (0.73) | CA1CA2ERN1TLR2TLR1 | |
| SCHEMBL470709 | 0.84 | CA1 (1.00) | CA1CA2ERN1TLR2TLR1 | |
| SCHEMBL419950 | 0.82 | ERN1 (0.76) | CA1CA2ERN1TLR2TLR1 | |
| SCHEMBL30485148 | 0.80 | ERN1 (1.00) | CA1CA2ERN1TLR2TLR1 | |
| SCHEMBL8598035 | 0.80 | CA1 (0.61) | CA1CA2ERN1TLR2TLR1 | |
| SCHEMBL16004 | 0.80 | ERN1 (1.00) | CA1CA2ERN1TLR2TLR1 | |
| SCHEMBL929734 | 0.80 | ERN1 (1.00) | CA1CA2ERN1TLR2TLR1 | |
| SCHEMBL22840376 | 0.79 | CA1 (0.56) | CA1CA2ERN1TLR2TLR1 | |
| SCHEMBL188094 | 0.78 | CA1 (0.65) | CA1CA2ERN1TLR2TLR1 | |
| SCHEMBL4450612 | 0.78 | ERN1 (0.96) | CA1CA2ERN1TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152778-A1 | HIGHLY ACTIVE CATALYSTS FOR ALKYLENE OXIDE POLYMERIZATION | Dow Global Technologies Inc. (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008134118-A1 | HIGHLY ACTIVE CATALYSTS FOR ALKYLENE OXIDE POLYMERIZATION | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-11-06 | — | — | WO | disclosed |