SCHEMBL27872145

SCHEMBL27872145

O=C(O)CCC#CI.O=C(O)Nc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
EPHX2 P34913 2/20 0.41
TP53 P04637 1/20 0.41
EPHX1 P07099 1/20 0.41
TSHR P16473 1/20 0.41
CDK9 P50750 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
MAPT P10636 2/20 0.40
HTT P42858 1/20 0.40
HSD17B10 Q99714 2/20 0.39
GAA P10253 2/20 0.39
PPARA Q07869 1/20 0.39
USP2 O75604 1/20 0.39
ABAT P80404 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2664415 0.76
Benzene SCHEMBL28162617 0.74 EPHX2 (0.70) CYP3A4EPHX2TP53EPHX1TSHR
SCHEMBL7634 0.74 EPHX2 (0.70) CYP3A4EPHX2TP53EPHX1TSHR
SCHEMBL560448 0.73 CYP1A2 (0.45) CYP1A2CYP3A4EPHX2TP53EPHX1
SCHEMBL10784058 0.73 EPHX2 (0.52) L3MBTL1CYP1A2CYP3A4CYP2D6EPHX2
SCHEMBL27872143 0.72 EPHX2 (0.42) L3MBTL1CYP1A2CYP3A4CYP2D6EPHX2
Hydrochloric Acid SCHEMBL9156069 0.72 EPHX2 (0.67) CYP3A4EPHX2TP53EPHX1TSHR
Water SCHEMBL9215017 0.72 EPHX2 (0.67) CYP3A4EPHX2TP53EPHX1TSHR
Bromide SCHEMBL5706299 0.72 EPHX2 (0.67) CYP3A4EPHX2TP53EPHX1TSHR
Fluoride SCHEMBL10885265 0.72 EPHX2 (0.67) CYP3A4EPHX2TP53EPHX1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104220505-B Fungicide formulations for plasticized PVC LANXESS DEUTSCHLAND GMBH (DE) 2016-06-01 CN claimed
CN-104220505-A Fungicide formulations for plasticized pvc LANXESS DEUTSCHLAND GMBH 2014-12-17 CN claimed
CN-102471526-A Polymers comprising heterocyclic 3-membered ring compounds and iodine-containing compounds LANXESS DEUTSCHLAND GMBH 2012-05-23 CN claimed
CN-102471526-A Polymers comprising heterocyclic 3-membered ring compounds and iodine-containing compounds LANXESS DEUTSCHLAND GMBH 2012-05-23 CN disclosed