SCHEMBL560448

SCHEMBL560448

O=C(O)Nc1ccccc1.OCCOCC#CI

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HSD17B10 Q99714 2/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
TSHR P16473 2/20 0.37
TP53 P04637 2/20 0.37
EPHX2 P34913 2/20 0.37
EPHX1 P07099 1/20 0.37
CDK9 P50750 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37
HPGD P15428 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560447 0.80 NPC1 (0.56) CYP1A2KDM4EALDH1A1MEN1KMT2A
SCHEMBL961817 0.76 HDAC3 (0.42) CYP1A2KDM4EALDH1A1HSD17B10MEN1
Carbamic Acid Phenyl Ester SCHEMBL1903915 0.76 MEN1 (0.40) ALDH1A1MEN1KMT2ARECQL
Carbamic Acid SCHEMBL9719090 0.74 POLB (0.35) ALDH1A1MEN1KMT2ATSHR
SCHEMBL961819 0.74 CYP1A2 (0.40) CYP1A2KDM4EALDH1A1HSD17B10MEN1
SCHEMBL677537 0.74 KMT2A (0.54) CYP1A2ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL10756079 0.74
SCHEMBL27872145 0.73 L3MBTL1 (0.46) CYP1A2HSD17B10MEN1KMT2ACYP3A4
SCHEMBL9266421 0.72 HDAC3 (0.44) CYP1A2KDM4EALDH1A1MEN1KMT2A
SCHEMBL7634 0.70 EPHX2 (0.70) ALDH1A1HSD17B10KMT2ACYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3167016-B1 NOVEL POLYSILOXANE-BASED FOULING-RELEASE COATS COMPRISING POLY(OXYALKYLENE)-MODIFIED ALCOHOLS HEMPEL AS (DK) 2025-06-04 EP disclosed
EP-2726561-B2 FOULING CONTROL COATING COMPOSITIONS HEMPEL AS (DK) 2025-05-07 EP disclosed
US-20250129254-A1 ACRYLATE COATING COMPOSITION FOR FORMING AN ANTIFOULING COAT HEMPEL A/S (DK) 2025-04-24 US disclosed
EP-4497794-A2 METHOD FOR ESTABLISHING A FOULING RELEASE COATING SYSTEM Hempel A/S (DK) 2025-01-29 EP disclosed
EP-3802709-B1 METHOD FOR ESTABLISHING A FOULING RELEASE COATING SYSTEM HEMPEL AS (DK) 2024-08-07 EP disclosed
EP-4399247-A1 ACRYLATE COATING COMPOSITION FOR FORMING AN ANTIFOULING COAT Hempel A/S (DK) 2024-07-17 EP disclosed
US-20240067835-A1 POLYSILOXANE-BASED FOULING CONTROL COATING SYSTEMS HEMPEL A/S (DK) 2024-02-29 US disclosed
US-11787953-B2 Polysiloxane-based fouling control coating systems HEMPEL A/S (DK) 2023-10-17 US disclosed
WO-2023139212-A1 CURABLE POLYSILOXANE COATING COMPOSITION COMPRISING POLYSILAZANE DANMARKS TEKNISKE UNIVERSITET (DK) 2023-07-27 WO disclosed
WO-2023036923-A1 ACRYLATE COATING COMPOSITION FOR FORMING AN ANTIFOULING COAT HEMPEL A/S (DK) 2023-03-16 WO disclosed
EP-0952194-A2 Antifouling paint composition J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1999-10-27 EP disclosed
EP-0789731-B1 SEA WATER-ERODIBLE ANTIFOULING PAINT COMPOSITION HEMPELS SKIBSFARVE FAB J C (DK) 1999-06-09 EP disclosed
EP-0900257-A1 ANTIFOULING PAINT J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1999-03-10 EP disclosed
WO-1997044401-A1 ANTIFOULING PAINT J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1997-11-27 WO disclosed
EP-0792326-A2 ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1997-09-03 EP disclosed
EP-0789731-A1 SEA WATER-ERODIBLE ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1997-08-20 EP disclosed
EP-0725563-A1 MARINE STRUCTURE J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1996-08-14 EP disclosed
WO-1996015198-A2 ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1996-05-23 WO disclosed
WO-1996014362-A1 SEA WATER-ERODIBLE ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1996-05-17 WO disclosed
WO-1995011592-A1 MARINE STRUCTURE J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1995-05-04 WO disclosed