SCHEMBL27872147

SCHEMBL27872147

c1ccc(-c2c3ccccc3c(-c3ccc4ccc(-c5ccc(-c6ccc7ccccc7c6)cc5)cc4c3)c3ccccc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.53
ESR2 Q92731 7/20 0.53
HSD17B1 P14061 2/20 0.48
HSD17B2 P37059 2/20 0.48
CYP17A1 P05093 1/20 0.46
CYP19A1 P11511 1/20 0.46
CYP11B1 P15538 1/20 0.46
CYP11B2 P19099 1/20 0.46
ALOX5 P09917 2/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2B6 P20813 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15366606 1.00 ESR1 (0.53) ESR1ESR2HSD17B1HSD17B2CYP17A1
SCHEMBL21346641 0.98 ESR1 (0.50) ESR1ESR2HSD17B1HSD17B2CYP17A1
SCHEMBL30991596 0.98 ESR1 (0.50) ESR1ESR2HSD17B1HSD17B2CYP17A1
SCHEMBL24444041 0.96 ESR1 (0.57) ESR1ESR2HSD17B1HSD17B2CYP17A1
SCHEMBL31355617 0.96 ESR1 (0.55) ESR1ESR2HSD17B1HSD17B2CYP17A1
SCHEMBL1013297 0.96 ESR1 (0.52) ESR1ESR2HSD17B1HSD17B2CYP17A1
SCHEMBL15366682 0.96 HSD17B1 (0.52) ESR1ESR2HSD17B1HSD17B2CYP17A1
SCHEMBL27889956 0.96 ESR1 (0.52) ESR1ESR2HSD17B1HSD17B2CYP17A1
SCHEMBL15366778 0.94 ESR1 (0.52) ESR1ESR2HSD17B1HSD17B2CYP17A1
SCHEMBL24174187 0.94 HSD17B1 (0.52) ESR1ESR2HSD17B1HSD17B2CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102659504-B Organic electric-field light-emitting element, display unit and lighting device JNC CORPORATION (JP) 2016-05-04 CN disclosed
CN-102659504-A Emission layer material, organic electroluminescence element, display device and lighting device JNC CORP 2012-09-12 CN disclosed