Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22942009 | 0.87 | BTK (0.46) | KDM1AMAOBBTKNFKB1NFKB2 | |
| SCHEMBL28310040 | 0.87 | BTK (0.49) | KDM1AMAOBBTKNFKB1NFKB2 | |
| SCHEMBL9078331 | 0.86 | NFKB1 (0.49) | KDM1AMAOBBTKNFKB1NFKB2 | |
| SCHEMBL20115731 | 0.86 | ESR2 (0.48) | KDM1AMAOBBTKCTSKKMT2A | |
| SCHEMBL26079223 | 0.82 | BTK (0.47) | KDM1AMAOBBTKNFKB1NFKB2 | |
| SCHEMBL15715158 | 0.80 | ESR2 (0.44) | KDM1AMAOBBTKNFKB1NFKB2 | |
| SCHEMBL15688927 | 0.80 | ESR2 (0.44) | KDM1AMAOBBTKNFKB1NFKB2 | |
| SCHEMBL15688929 | 0.80 | ESR2 (0.44) | KDM1AMAOBBTKNFKB1NFKB2 | |
| SCHEMBL22776716 | 0.79 | BTK (0.48) | KDM1AMAOBBTKNFKB1NFKB2 | |
| SCHEMBL28870402 | 0.79 | BTK (0.48) | KDM1AMAOBBTKNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925304-A | Compound for preparing kalilazine and preparation method thereof | 江苏恩华药业股份有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-105985335-A | Hydroxamic acid compound, preparation method and application thereof | 成都地奥九泓制药厂 | 2016-10-05 | — | — | CN | disclosed |
| CN-102659630-B | A kind of hydroxamic acid compound and its production and use | CHENGDU DIAO JIUHONG PHARMACEUTICAL FACTORY (CN) | 2016-01-06 | — | — | CN | disclosed |
| CN-102659630-A | Hydroxamic acid compound and preparation method as well as application thereof | CHENGDU DIAO JIUHONG PHARMACEUTICAL FACTORY | 2012-09-12 | — | — | CN | disclosed |