Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22793161 | 0.77 | — | — | |
| SCHEMBL3407152 | 0.74 | — | — | |
| SCHEMBL13762916 | 0.74 | — | — | |
| SCHEMBL3103050 | 0.74 | — | — | |
| SCHEMBL16585834 | 0.74 | — | — | |
| SCHEMBL14665033 | 0.73 | CYP2D6 (0.32) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL28495057 | 0.72 | — | — | |
| SCHEMBL19718510 | 0.69 | ARG1 (0.30) | ARG1 | |
| SCHEMBL3548986 | 0.68 | CRBN (0.33) | — | |
| SCHEMBL2004047 | 0.68 | ARG1 (0.33) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102427726-B | fused ring inhibitors of hepatitis c | PRESIDIO PHARMACEUTICALS, INC. (US) | 2014-10-08 | — | — | CN | disclosed |
| CN-102427726-A | Fused ring inhibitors of hepatitis c | PRESIDIO PHARMACEUTICALS INC | 2012-04-25 | — | — | CN | disclosed |